How to Get Paint Out of Clothing: To remove paint from clothing, act quickly. For water-based paints, rinse the affected area with warm water and gently rub the stain. Apply liquid dish soap or laundry detergent directly to the stain and work it into a lather. Rinse and repeat as needed. For oil-based paints, use a solvent like rubbing alcohol or nail polish remover. Dab the stain with a cloth soaked in the solvent, then wash the garment as usual. It’s important to check the fabric care label and test any product on a small, inconspicuous area before proceeding.