How to Remove Lice from Hair Permanently: To effectively remove lice from hair permanently, it’s important to use a combination of treatments. Start by using a lice comb to physically remove the lice and their eggs (nits) from the hair. Next, apply an over-the-counter or prescription lice treatment shampoo or lotion according to the instructions. It’s crucial to treat all affected individuals simultaneously and thoroughly clean bedding, clothing, and personal items. Regularly combing the hair with a lice comb and repeating the treatment as directed can help ensure complete removal and prevent reinfestation.