Elysian Moisturizer Do you have eczema? There are easy ways to help lessen its impact. Avoid anything, like lotion or laundry detergents, that contains perfume. Second, only wear clothes made of cotton. Fabrics like wool or synthetics like rayon could worsen your eczema. Third, make sure you only use makeup with natural ingredients and no dyes. These things can help prevent any additional skin irritation, which could result in a terrible flare-up.